Thursday 20 February 2014

MULTI-DRUG RESISTANT TUBERCULOSIS: A PROSPECTIVE STUDY

Author Name:  *PRIYA SANTHARAM and APPALARAJU B
Volume No : 1,  Issue No : 1,  Published year : 2014, Category : Biological Sciences

Abstract:
Objective: The prospective study was done to determine the incidence of Multidrug resistant tuberculosis at our Tertiary care Hospital in South India.
Materials and methods: Smear positive respiratory samples collected over a period of one year were processed for detection of M.tuberculosis, using standard methods and subjected to susceptibility for 2 drugs - Isoniazid and Rifampicin by Absolute concentration method.
Results: Out of the117 smear positive respiratory samples collected, M.tuberculosis grew in 101 samples. Our study showed primary and acquired resistance for both drugs to be 1.25% and 19% respectively.
Conclusion: Finally our study showed MDR-TB to be present more in default patients than new cases. The data was in accordance with the prevalence values available from Indian and global studies.

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